Robust model systems for pancreatic diseases allow you to effectively investigate disease pathology or identify and evaluate new drug treatments.

This validated workflow achieves high differentiation efficiency for human iPSC-derived pancreatic duct-like organoids (PDLOs), with multiple analyses demonstrating structural and functional relevance.

• Flow cytometry confirms highly efficient ductal cell marker expression
• Immunofluorescent staining finds correct localization of markers across stages of differentiation
• CFTR assays show functional CFTR ion channels
• Treatment with CFTR inhibitors underscores usefulness as a drug screening platform