Lonza launches New Non-Endotoxin Pyrogen Detection System PyroCell® MAT Human Serum System Kit
The Monocyte Activation Test (MAT) is an in vitro assay for pyrogen testing in pharmaceutical and medical device industries based on the detection of inflammatory cytokine (IL-6) released by human monocyte in reponse to exogenous bacterial endotoxin (LPS) and non-endotoxin pyrogens (NEP). As such, the MAT offers an ideal solution to replace the rabbit pyrogen test , thereby reducing reliance on experimental animals.
Lonza has launched new non-endotoxin pyrogen detection system PyroCell® MAT Human Serum System Kit and this new in vitro pyrogen testing system exhibits enhanced sensitivity for detection of non-endotoxin pyrogens (NEP) as well as reduced interferences from complex drug products such as biologics-based pharmaceutical.
Customer can now choose the best pyrogen test for their specific need and take advantage of Lonza's expert technicial service to support implementation and optimize testing processes.